web metrics

Archive for August, 2008

Engineers create bone to blend with tendons

Sunday, August 31st, 2008

Engineers have used skin cells to create artificial bones that mimic the ability of natural bone to blend into other tissues such as tendons or ligaments.

The artificial bones display a gradual change from bone to softer tissue rather than the sudden shift of previously developed artificial tissue, providing better integration with the body and allowing them to handle weight more successfully.

“One of the biggest challenges in regenerative medicine is to have a graded continuous interface, because anatomically that’s how the majority of tissues appear and there are studies that strongly suggest that the graded interface provides better integration and load transfer,” said Andres Garcia, professor at George W. Woodruff School of Mechanical Engineering at the Georgia Institute of Technology.

Garcia and former graduate student Jennifer Phillips, along with research technician Kellie Burns and their collaborators Joseph Le Doux and Robert Guldberg, were not only able to create artificial bone that melds into softer tissues, but were also able to implant the technology in vivo for several weeks.

“Every organ in our body is made up of complex, heterogeneous structures, so the ability to engineer tissues that more closely mimic these natural architectures is a critical challenge for the next wave of tissue engineering,” said Phillips, who is now working at Emory University as a postdoctoral research fellow in developmental biology.

The research appeared in the Aug 26 edition of the Proceedings of the National Academy of Sciences.

Laser used in surgery for brain cancer

Saturday, August 30th, 2008

In a ground-breaking advance, French neurosurgeons on Friday said they had successfully treated brain tumours through ultra-keyhole surgery, using a tiny fibre-optic laser to destroy cancerous cells.

Alexandre Carpentier of the Pitie-Salpetriere Hospital in Paris said the exploit was “a world-first” in its use of multiple advanced techniques and of local anaesthesia rather than general sedation.

So far, eight volunteers have been treated in the pilot programme, launched December 2006, Carpentier told media.

“They were suffering from metastasing brain tumours caused by various cancers, mainly lung and breast cancer that failed to respond to conventional treatment and were otherwise inoperable,” he said.

Doctors had given the volunteers only three months left to live, on average.

Under the pioneering technique, a minute hole three millimetres (0.12 of an inch) wide was drilled into the skull, allowing the surgeon to introduce a water-cooled fibre-optic laser into the brain.

The device was gently guided towards the tumour area with the help of a magnetic resonance imaging (MRI) scanner.

Every three seconds, a computer workstation calculated the temperature at the area being burned by the laser to ensure that there was no dangerous overheating and to confirm that only tumorous cells were being destroyed.

The patient received only a local anaesthetic, remaining conscious in order to be able to speak to the medical team to help verify that cerebral functions were not being harmed.

However, “the patients feels nothing during the operation and generally can leave hospital 14 hours later, the evening or the morning after the operation,” the surgeon said.

The results are “conclusive,” said Carpentier.

Treating the patients completely requires two or more bouts of surgery, and there had been no cases of cerebral bruising or epilepsy.

So far, six of the eight have completed the full programme. Of the six, five have not had a relapse — a return of cancerous cells to the brain — at a nine-month monitoring point.

“This is the first time that laser technology has been used intracranially, meaning inside an enclosed skull, using MRI in real time to avoid collateral damage,” said Carpentier.

“This is the forerunner of future techniques in which MRI will play a core intervention role in neurosurgery.”

The pilot trial, reported in the latest issue of the US journal Neurosurgery, was carried out under the supervision of the French Health Products Safety Agency (AFSSAPS).

It drew on advanced technology supplied by the MD Anderson Cancer Center in Houston, and a Texan company, BioTex Inc, which specialises in the use of lasers for medical therapy.

Nintendo lifts profit, shares soar

Saturday, August 30th, 2008

Nintendo Co boosted its annual profit outlook by 23 percent on white-hot demand for its Wii video game console and DS portable player, beating market expectations and sending its shares more than 8 percent higher.

As consumers in the United States and Europe snap up its game machines, Nintendo hiked forecasts for the Wii 6 percent and for the DS 9 percent, pushing the company to the limits of current production capacity.

“The fact that Nintendo is confident to say even before the end of the first half, that overseas sales are this strong, will likely help the stock ride a wave towards the Christmas shopping season,” said Koki Shiraishi, an analyst at the Daiwa Institute of Research.

The Wii, launched in late 2006, has far outsold Sony’s PlayStation 3 and Microsoft’s Xbox 360 in the $57 billion video game industry, thanks to its easy-to-learn motion-sensing controller, low price and innovative titles like the “Wii Fit” exercise game.

Nintendo said it now expects an operating profit of 650 billion yen ($6 billion) in the year to March, up from its previous forecast of 530 billion yen, also helped by a softer yen.

It sees sales of 2 trillion yen, 11 percent higher than its previous estimate.

The new profit forecast trounced a Reuters Estimates consensus of 605 billion yen from 20 analysts.

Nintendo’s shares rose by their daily limit of 4,000 yen to close at 51,800 yen, outperforming a 2.4 percent climb for the Nikkei benchmark

The stock’s value grew more than five-fold in the two years through October 2007, spurred by strong sales of the DS and Wii, Nintendo’s twin growth engines.

But it has lost 28 percent since then due to investor concerns that its break-neck growth may be slowing.

The company lifted its annual dividend forecast to 1,680 yen, up from the 1,370 yen it had expected in April. It also lifted its half-year operating profit estimate by 17 percent to 245 billion yen.

Nintendo’s robust sales underscores the video game sector’s resilience in the face of soaring oil prices and sluggish consumer spending which have hurt industries such as autos.

“Games aren’t all that expensive, so they’re appealing even now. Something like a car, of course, is quite different,” Shinkin Asset Management fund manager Tomomi Yamashita said.

By contrast, Toyota Motor Corp cut its 2009 vehicle sales forecast on Thursday.

Nintendo said it now aims to sell 26.5 million Wii consoles and 30.5 million DS players this business year.

Want IE8 Beta 2? You May Have To Jump Through Hoops

Saturday, August 30th, 2008

Microsoft warned developers preparing to download the new Beta 2 release of Internet Explorer 8 that under certain conditions those who have already installed IE8 Beta 1 cannot revert to older iterations of the browser.

For Windows XP users with IE8 Beta 1 already installed, Windows XP Service Pack 3 and IE8 Beta 2 would become permanent, said Jane Maliouta, the deployment product manager for IE8 at Microsoft. “You will still be able to upgrade to later IE8 builds as they become available, but you won’t be able to uninstall them,” she said.

Incompatibility Issues

Developers will need to be careful because IE8 Beta 2 will not work with several key services, applications and add-on programs, including certain versions of the Windows Live Mail. IE8 Beta 2 users also are currently unable to view movies on demand from Netflix, though Microsoft said the two companies are working to resolve the compatibility issue as quickly as possible.

Maliouta strongly encouraged those who have already downloaded IE8 Beta 1 to follow several steps before installing the new Beta 2 version. First uninstall the Beta 1 version and SP3 for Windows XP, followed by reinstalling SP3, and only then install IE8 Beta 2.

“If you have IE8 Beta 1 installed, the IE8 installer will automatically uninstall any earlier versions and then install the latest version of IE8 Beta 2 for you,” Maliouta said. “You will be prompted to reboot twice. The first reboot is to remove IE8 Beta 1 from your machine and the second one to complete the IE8 Beta 2 installation.”

According to Microsoft, IE8 Beta 1 was only intended for use by developers. Consumers running Windows XP need not worry about downloading IE8 Beta 2 so long as they did not install Beta 1.

However, consumers testing IE8 Beta 2 on their Vista-enabled machines must jump through a few hoops should they decide to revert to IE7. According to Microsoft, they’ll have to click the Start button, type “Programs and Features” in the Start Search box, and click Programs and Features in the Programs list. Then in the Tasks pane, they’ll need to click “View installed updates,” select IE8 Beta 2 and then click “Uninstall.”

Dueling Releases

The relatively unpolished state of IE8 Beta 2 is not all that unusual. Early versions of Firefox 3 likewise were subject to various compatibility issues and performance limitations.

Both Mozilla and Microsoft are doing all they can to gain browser market share. For example, Mozilla’s recent release of its “experimental” Ubiquity plug-in is an attempt to steal some of the thunder from some new features destined for IE8, called Accelerators and Web Slices. For its part, Microsoft has already added several new capabilities to IE8 Beta 2 that mimic what Firefox 3 already has on tap, including the rival browser’s so-called “AwesomeBar.”

Mozilla’s campaign to set a world software-download record for Firefox 3 earlier this year has increased the pressure on Microsoft to turn the tide. Though the software giant has stabilized its market-leading share of the browser market in the last three months, Microsoft’s numbers have fallen seven percentage points in the past 12 months, and 24.5 percentage points since August 2005, according to a new global survey conducted by Janco and the IT Productivity Center.

Millions of young Chinese addicted to ‘unhealthy’ Internet games: report

Saturday, August 30th, 2008

Around four million Chinese youngsters are addicted to the Internet, mainly attracted by “unhealthy” online games, state media reported Friday, citing a top legislator.

“Internet-addicted teenagers” account for around 10 percent of China’s Web users under the age of 18, the Beijing Times said, quoting Li Jianguo, a vice chairman of the standing committee of the National People’s Congress, or parliament.

The committee has called for stricter monitoring of Internet games that have illegal or inappropriate content, the report said.

It has also said games should include technology that automatically logs players off once they exceed a set number of hours of continuous play.

“Unhealthy” games by Chinese government standards could refer to those featuring violence and pornography as well as “unpatriotic games” that make Chinese soldiers or agents the enemy.

The government has tried various measures to regulate the booming online gaming market and curb teenagers’ use of Internet games.

In 2006, it ordered all Chinese Internet game manufacturers to install technology in their games that demands players reveal their real name and identification number.

Microsoft to drop $486 million for European shopping site

Friday, August 29th, 2008

Microsoft said Friday it has reached a deal to acquire Greenfield Online, the owner of consumer shopping sites, for about $486 million.

Greenfield’s properties include Munich, Germany-based Ciao, one of the leading price-comparison and online-shopping sites in Europe. Ultimately, Microsoft said, Ciao’s technology platform, online community, and merchant relationships will be integrated with Microsoft’s Live Search.

Ciao features consumer reviews and ratings. Microsoft said that, according to ComScore, Ciao has more than 26.5 million unique visitors per month across seven countries, who have generated more than 5 million product reviews.

The deal calls for Microsoft to commence a cash tender offer to purchase all of the outstanding shares of Greenfield for $17.50 per share, or roughly $486 million.

Wilton, Conn.-based Greenfield, which acquired Ciao in 2005, also owns an Internet survey business, which Microsoft plans to sell off. Microsoft said it has already secured an unnamed buyer for that unit.

Both transactions are expected to close during the fourth quarter.

Microsoft’s offer for Greenfield trumps an earlier deal. In June, Greenfield said it was in takeover discussions with the Quadrangle Group and had secured an agreement to be acquired for $15.50 per share.

In a press release issued on Friday, Greenfield said that “immediately prior to entry into the merger agreement with Microsoft it had terminated its previously announced merger agreement with affiliates of Quadrangle Group LLC.”

In connection with the termination of that deal, Greenfield said it is required to pay Quadrangle a $5 million fee.

‘Ratchet & Clank’ leads wave of fresh PSN games

Friday, August 29th, 2008

Of the three video-game console manufacturers, Microsoft was the first to embrace online gaming, and its Xbox Live has become essential to anyone who wants to play against faraway competitors. Sony and Nintendo are trying to catch up with, respectively, the PlayStation Network and the Virtual Console.

PSN has more momentum. It’s already home to solid multiplayer games like “Warhawk” and “Metal Gear Online,” and future projects like “Home,” “DC Universe Online” and “MAG” (a 256-player war game) promise to stretch Internet-connected play in innovative ways.

Sony also lets you download games directly to your PS3 hard drive. The library isn’t as impressive as Microsoft’s or Nintendo’s, but there are some gems (”Echochrome,” “PixelJunk Monsters“) that you can find only on PSN. Each of the three games reviewed here brings some fresh ideas to the network, and may provide some hints of what’s in store for PlayStation diehards.

_”Ratchet & Clank Future: Quest for Booty” (Sony, for the PlayStation 3, $15): At the end of last year’s “Tools of Destruction,” Clank disappeared with a tribe of his fellow robots. As this new chapter begins, Ratchet (the furry half of the duo) discovers that the pirate Captain Darkwater may know where Clank went. Unfortunately, Darkwater is dead, so Ratchet must search for the scurvy seadog’s treasure in hopes of finding a clue.

“Quest for Booty” plays like a stripped-down version of its predecessor, leaving out all the side missions and minigames in favor of straight-ahead action. Even Ratchet’s impressive arsenal of wacky weapons has been scaled back: For much of the game, his only tool is his trusty wrench. There are still plenty of nifty puzzles and running-and-jumping action, though, so things never slow down.

For a project that’s really a stopgap between full-fledged “R&C” adventures, “Quest for Booty” still delivers the brilliant animation and screwball humor we’ve come to expect from the developers at Insomniac Games. It only takes about three hours to finish, but it’s a tasty appetizer until the next main course arrives in 2009. Three stars out of four.

_”PixelJunk Eden” (Sony, for the PlayStation 3, $10): The Kyoto, Japan-based Q-Games has released three very different titles for PSN: the slot-car game “PixelJunk Racers,” the strategy gamePixelJunk Monsters,” and the uncategorizable “PixelJunk Eden,” which looks like no game you’ve ever seen before.

Each level begins in an underpopulated garden with a minuscule hero who can swing and jump from leaf to leaf. When he swings into a “prowler,” it releases pollen, which helps more plants grow. The goal is to grow the plants high enough to reach the prized “Spectra.”

The psychedelic visuals and techno soundtrack give “PixelJunk Eden” a trippy vibe, but its controls take some getting used to and may frustrate casual gamers at first. Also frustrating is a very unforgiving timer, which forces you to rush through levels instead of allowing you to admire your gardening skills. Still, the deeper you get into “Eden,” the more satisfying it becomes, with challenges that cleverly expand upon the minimalist approach of the early levels. Three stars.

_”Siren: Blood Curse” (Sony, for the PlayStation 3, $15 for four episodes, $40 for 12 episodes): In an interesting experiment in episodic gaming, Sony has retooled the overlooked 2004 title “Siren,” chopped it up into a dozen chapters and set them loose on PSN. The graphics aren’t much better then they were are the PlayStation 3, but the developers have tightened up the gameplay and added some American characters.

In the first episode, a U.S. camera crew stumbles across a Japanese village populated by zombies, and you briefly assume the role of a college student who’s trying to escape from an undead cop. In later episodes you see the events in the village through different characters’ eyes — at times, even through the eyes of the zombies themselves.

It’s an effective survival horror adventure, but the episodic structure doesn’t help, mainly because the individual chapters take so long to download and install. Also, the early chapters are very short (about 20 minutes), which may dissuade cost-conscious players from downloading the entire run. I’m hoping Sony takes more chances on episodic games, but next time its developers need to build one from scratch. Two stars.

Bloomberg mistakenly publishes Steve Jobs obituary

Thursday, August 28th, 2008

An electronic gaffe at news outlet Bloomberg mistakenly sent an incomplete obituary for Apple CEO Steve Jobs over the wire on Wednesday afternoon, and a tipster promptly sent the soon-retracted file to gossip blog Gawker.

The lengthy file contains not only a preliminary obituary for the iconic Apple chief, but also a list of suggested contacts for a more extensive story–Apple co-founder Steve Wozniak, Oracle CEO Larry Ellison, and early Apple evangelist Guy Kawasaki, among others.

The summary of Jobs’ accomplishments, per the obituary, is that he “helped make personal computers as easy to use as telephones, changed the way animated films are made, persuaded consumers to tune into digital music, and refashioned the mobile phone.”

It’s not out of the ordinary at all that Bloomberg would have this written; all major news outlets have notable persons’ obituaries prepared in advance so that only minor changes need be made at the actual time of death. That way, the news can be reported almost immediately and can be updated with further detail.

But a Jobs obituary, however premature, is more chilling than, say, a Bill Gates obituary. The Apple CEO successfully battled pancreatic cancer earlier this decade, and a magazine profile indicated that he had kept it secret for nine months while researching alternative treatments–a questionable move for any chief executive of a publicly traded company, but especially one as crucial to the runnings of the business as Jobs is.

When Jobs appeared onstage at the Worldwide Developers Conference in June 2008, his thin appearance led some bloggers and company critics to speculate that he was ill again, and some of them pushed the bounds of decency in demanding that Apple reveal the state of the executive’s health to shareholders.

So given a CEO whose health has been discussed so speculatively in the echo chamber of the blogosphere, and whose company’s stock has been shown to be far from immune to the influence of the rumor mill, the appearance–however brief–of a Jobs obituary online must certainly have been disquieting for those who stumbled upon it.

Bloomberg released a retraction later on Wednesday that made only the vaguest of reference to the content of the gaffe. “An incomplete story referencing Apple Inc. was inadvertently published by Bloomberg News at 4:27 p.m. New York time today,” the retraction read. “The item was never meant for publication and has been retracted.”

Mystery Chinese iPhone worker becomes Internet star

Thursday, August 28th, 2008

A Chinese factory worker has become an Internet sensation after a picture of her smiling and flashing a peace sign to a co-worker testing an Apple iPhone stayed on the phone that was sold to a man in Britain.

Photos of the unidentified, smiling woman were posted on the Apple discussion website MacRumours.com by a customer identified as “markm49uk” from Kingston-upon-Hull and quickly posted around other sites.

“Not sure if this is or is not the ‘norm’ but I just received my brand new iPhone here in the UK and once it had been activated on iTunes I found that the home screen (the screen you can personalize with a photo) already had a photo set against it!!!!” he wrote.

“It would appear that someone on the production line was having a bit of fun - has anyone else found this?”

Some people voiced concern that the woman could now lose her job while others joked on the website that they were considering returning their phones because they did not come loaded with a photo.

“I think its a kind of personal touch. It’s nice. Maybe every phone that gets a full quality test should have its tester’s picture taken and left on there. And the working conditions look pretty good,” wrote one.

Taiwanese company Foxconn assembles the iPhones for Apple in Shenzhen in southern China but calls to the company by Reuters went unanswered.

However Foxconn spokesman Liu Kun told the South China Morning Post in Hong Kong that the woman had been identified but her details would not be released. She had also been assured by her bosses that her job was safe.

Liu said the photos were taken in the testing department as part of a normal procedure and only one phone was known to be affected so far.

Democratic bloggers shun official digs for ‘Big Tent’

Wednesday, August 27th, 2008

If you want to find bloggers here at the Democratic convention, don’t look inside the Pepsi Center, an island of concrete surrounded by fences, barriers, checkpoints, and heavily armed police in helmets and black uniforms.

Many have camped out in a more welcoming place: the so-called Big Tent, located a few blocks outside the security perimeter where bloggers can pay $100 for a place to work for the week. There are free smoothies and massages downstairs (thanks to Google) and free lectures upstairs (courtesy of left-leaning activists hoping to rally the faithful).

It is true that the Democratic National Convention Committee handed credentials to a record number of bloggers for the Denver convention this week, but more nevertheless appear to have gathered at the Big Tent. Adding to the lure of the unofficial venue is that the workspace’s location on Wynkoop Street is around the corner from a multitude of restaurants and private parties, including a massive Tuesday reception organized by Emily’s List, a late-night jazz festival, and an AT&T-sponsored brewery bash.

Sara Robinson, a self-described progressive blogger from Vancouver, B.C., received credentials for both the Pepsi Center and the Big Tent. Her DNCC credentials got her prime seating during Michelle Obama’s speech on Monday night.

“I was in front of the front row last night,” said Robinson, who’s blogging for Campaign for America’s Future, a Washington-based advocacy group, and liberal lifestyle site Group News Blog. “There was nothing between me and the Secret Service.”

The DNCC designated an official “blogger lounge” inside the Pepsi Center–the location for convention events except for Barack Obama’s speech on Thursday–with access to televisions and other technology resources. The credentialed bloggers also have access to the convention floor, press briefing areas, caucus meetings, filing centers, and other auxiliary events open to members of the media.

Even though she said she appreciated her floor access, which is sometimes difficult to obtain for mainstream media, Robinson was less than impressed with the blogger lounge.

“Last night, before I went to the floor, I saw that there’s a press room–it’s lovely, it’s air conditioned,” she said. “Then there’s a little room off to the side, and it’s dark and it’s dank. We’re clearly not allowed to mingle with the big kids. I’m hoping in 2008 or 2012 we’ll get past that.”

The Big Tent is not without its flaws, though. The 8,000-square-foot, two-story structure is notably lacking efficient air conditioning, Robinson pointed out.

“Other than that, it’s amazing we have our own space,” she said. “Physical presence counts for a lot. In 2004 there were bloggers, but we didn’t have a space. What it says is, ‘We are here, we are present, in a way we haven’t been before.’

“It’s an interesting time to meet my fellow bloggers and learn a lot more about how the sausage gets made,” she continued. “It’s fun to be part of a community that’s merging into its own in the progressive community.”

Other international bloggers, including Panayotis Vryonis from Greece, joined Robinson in the Big Tent. As a social media consultant for a progressive party from his country, Vryonis said this “was a good opportunity to see what’s going on.”

“You guys are a couple years ahead of us as far as the use of Internet in politics,” he said.

Vryonis said that with only about 25 percent of Greek households connected to the Internet, campaigning online in Greece is not as effective as in the United States.

“With raising money, people have to be used to using their credit card online or used to giving their e-mail out,” he said. “It’s not about technology, per se– it’s more a cultural thing.”

Vryonis said he paid his own way for the trip to Denver to write about it firsthand on his blog Vrypan.net.

“I’m not making money out of (blogging), but it’s not exactly a hobby since it helps my job,” he said.

Through his connections in the Greek-American community, Vryonis was able to get DNCC credentials as well.

“The access to the convention center is the most important thing, if you want to be able to say you attended,” he said, “but to be honest, (the Big Tent) is much better.”

The outcome of the U.S. election will influence not only Greek politics but European politics in general, Vyronis said. “There’s an Obama-mania in Greece and Europe in general,” he said. “The media loves him, and bloggers love him too, since he’s used the Internet in his campaign. I hope he keeps them mesmerized after the election if he gets elected, when it really becomes difficult.”

Larisa Thomason, a blogger for Left in Alabama, initially supported John Edwards, who has recently been embroiled in a scandal involving him cheating on his wife.

“I spent a week in Iowa with my 14-year-old daughter, freezing our butts off for John Edwards,” she said. “His platform was the most progressive.”

“I live in a place in Alabama where I can’t get cell phone access from my house, and I can’t use wireless Internet because we don’t have broadband out in the country,” Thomason said. “Edwards spoke to those issues. When Edwards pulled out, I just kind of checked out and waited to see” who the Democratic candidate would be.

A Web content writer by profession, Thomason blogs voluntarily for Left in Alabama and paid her own way to Denver, along with three other Left in Alabama bloggers. They held an online fundraiser for the trip on their site, which has seen its readership grow from a couple hundred readers per day last winter to about 1,000 readers a day. The site raised enough money to cover the $100 Big Tent fee for all four bloggers.

“That was really nice because it made us realize people actually care what we’re writing and want to hear from us,” she said.

Left in Alabama also received DNCC credentials and was offered media housing by the DNCC.

“The room we were offered was $45 a night, so we jokingly referred to it as the ‘blogger crackhouse,’” Thomason said.

Thomason opted to share a hotel room with a friend who is an Alabama delegate.

“One of our bloggers is staying at (the media housing), though, and he said it’s basic economy lodging, and we would’ve been fine there,” she said.

Left in Alabama received further credibility from the Library of Congress, which recently asked to use the blog for an archive of 2008 online political coverage it is creating, Thomason said.

The blogger has also been able to support the local media. The Huntsville Times of Alabama asked Thomason to contribute coverage of the Alabama delegation to the paper.

She has used her trip for more than just convention coverage, though. She arrived in Colorado early to take a detour to the Focus on the Family headquarters in nearby Colorado Springs, so she could write a “snarky” blog post about the conservative group.

Thomason also admitted she missed the first night of convention speeches on Monday.

“I wish I could tell you I was a good political blogger,” she said. “I was actually across town eating Ethiopian food. You don’t get it in Alabama!”